“structural and regulatory elements of genes”

“structural and regulatory elements of genes”

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Can anyone please explain a little about these two elements of genes? My main problem is with "which 'switch on' instructions".

genes have structural elements (which code for a particular protein) and regulatory elements (which 'switch on' instructions)

The expression of protein coding genes happens by the process of transcription. So promoters facilitate access of the RNA polymerase complex to DNA to begin transcribing a locus on the genome. The promoter of a gene often contains sequences that bind proteins called transcription factors, which play a role in various parts of the transcriptional process as well as components of RNA polymerase themselves (Such as a Pribnow box in prokaryotes, or a TATA box or an initiator element in animals).

So whether a gene is turned on and if so, how much it is turned on, is a property of how many transcription factor binding sites exist in the promoter, the nature of the transcription factors themselves in terms of their influence on transcription, and in eukaryotes and some archaea, epigenetic processes that control the access of transcriptional machinery to the locus being transcribed.

So when you think about the two elements in a gene, think of a light (the bit of a gene that codes for proteins) and a dimmer (which controls how much RNA is made by the protein-coding bit)

A structural element is that part of the gene that is giving the code to specify an amino acid that's going to be translated into a protein. A lot of the rest of the code may say "start reading here" "stop reading" "ribosome bind here" etc.

Watch the video: Εισαγωγή στα δικτυώματα, ελαφριά προσέγγιση των μέθοδων κόμβων και τομών Τεχνική Μηχανική 1-2 (May 2022).


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